Research
Publications
Full list of peer-reviewed papers, reviews, and book chapters from the lab.
Comprehensive Analysis of Extracellular Matrix Remodelling via Cyclophilin Inhibition in Human Models of Alcohol-Related Liver Fibrosis
Rastovic U, Campinoti S, Wei L, Almeida B, Bozzano SF, Amiri R, Harris N, Ajayi O, Koay TS, Kerins C, et al.
British Journal of Pharmacology · 2025
Human Precision-Cut Liver Slices: A Potential Platform to Study Alcohol-Related Liver Disease
Rastovic U, Bozzano SF, Riva A, Simoni-Nieves A, Harris N, Miquel R, Lackner C, Zen Y, Zamalloa A, Menon K, et al.
International Journal of Molecular Sciences · 2023
Patient-Derived Precision Cut Tissue Slices from Primary Liver Cancer as a Potential Platform for Preclinical Drug Testing
Jagatia R, Doornebal EJ, Rastovic U, Harris N, Feyide M, Lyons AM, Miquel R, Zen Y, Zamalloa A, Malik F, et al.
2023
Giant Mitochondria in Human Liver Disease
Shami GJ, Samarska IV, Koek GH, Li A, Palma E, Chokshi S, Wisse E, Braet F
Liver International · 2023
Human Immunocompetent Model of Neuroendocrine Liver Metastases Recapitulates Patient-Specific Tumour Microenvironment
Doornebal EJ, Harris N, Riva A, Jagatia R, Pizanias M, Prachalias A, Menon K, Preziosi M, Zamalloa A, Miquel R, et al.
Frontiers in Endocrinology · 2022
Extracellular Vesicle-Mediated Mitochondrial Reprogramming in Cancer
Carles-Fontana R, Heaton N, Palma E, Khorsandi SE
Cancers · 2022
Interplay between Cellular and Non-Cellular Components of the Tumour Microenvironment in Hepatocellular Carcinoma
Sükei T, Palma E, Urbani L
Cancers · 2021
Soluble TIM3 and Its Ligands Galectin-9 and CEACAM1 Are in Disequilibrium During Alcohol-Related Liver Disease and Promote Impairment of Anti-Bacterial Immunity
Riva A, Palma E, Devshi D, Corrigall D, Adams H, Heaton N, Menon K, Preziosi M, Zamalloa A, Miquel R, et al.
Frontiers in Physiology · 2021
Perturbations in Mitochondrial Dynamics Are Closely Involved in the Progression of Alcoholic Liver Disease
Palma E, Riva A, Moreno C, Odena G, Mudan S, Manyakin N, Miquel R, Degré D, Trepo E, Sancho-Bru P, et al.
Alcoholism: Clinical and Experimental Research · 2020
Dynamin-1-Like Protein Inhibition Drives Megamitochondria Formation as an Adaptive Response in Alcohol-Induced Hepatotoxicity
Palma E, Ma X, Riva A, Iansante V, Dhawan A, Wang S, Ni HM, Sesaki H, Williams R, Ding WX, et al.
American Journal of Pathology · 2019
Precision-Cut Liver Slices: A Versatile Tool to Advance Liver Research
Palma E, Doornebal EJ, Chokshi S
Hepatology International · 2019
Deficient IL-6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis
Stärkel P, Schnabl B, Leclercq S, Komuta M, Bataller R, Argemi J, Palma E, Chokshi S, Hellerbrand C, Maccioni L, et al.
Hepatology Communications · 2019
Osteopontin Is a Proximal Effector of Leptin-Mediated Non-Alcoholic Steatohepatitis (NASH) Fibrosis
Coombes JD, Choi SS, Swiderska-Syn M, Manka P, Reid DT, Palma E, Briones-Orta MA, Xie G, Younis R, Kitamura N, et al.
Biochimica et Biophysica Acta · 2016
Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients with Acute Alcoholic Hepatitis
Markwick LJL, Riva A, Ryan JM, Cooksley H, Palma E, Tranah TH, Manakkat Vijay GK, Vergis N, Thursz M, Evans A, et al.
Gastroenterology · 2015
NIM811, a Cyclophilin Inhibitor without Immunosuppressive Activity, Is Beneficial in Collagen VI Congenital Muscular Dystrophy Models
Zulian A, Rizzo E, Schiavone M, Palma E, Tagliavini F, Blaauw B, Merlini L, Maraldi NM, Sabatelli P, Braghetta P, et al.
Human Molecular Genetics · 2014
Critical Evaluation of the Use of Cell Cultures for Inclusion in Clinical Trials of Patients Affected by Collagen VI Myopathies
Sabatelli P, Palma E, Angelin A, Squarzoni S, Urciuolo A, Pellegrini C, Tiepolo T, Bonaldo P, Gualandi F, Merlini L, et al.
Journal of Cellular Physiology · 2012
A Glutamine Synthetase Inhibitor Increases Survival and Decreases Cytokine Response in a Mouse Model of Acute Liver Failure
Jambekar AA, Palma E, Nicolosi L, Rasola A, Petronilli V, Chiara F, Bernardi P, Needleman R, Brusilow WSA
Liver International · 2011
Genetic Ablation of Cyclophilin D Rescues Mitochondrial Defects and Prevents Muscle Apoptosis in Collagen VI Myopathic Mice
Palma E, Tiepolo T, Angelin A, Sabatelli P, Maraldi NM, Basso E, Forte MA, Bernardi P, Bonaldo P
Human Molecular Genetics · 2009
The Cyclophilin Inhibitor Debio 025 Normalizes Mitochondrial Function, Muscle Apoptosis and Ultrastructural Defects in Col6a1-/- Myopathic Mice
Tiepolo T, Angelin A, Palma E, Sabatelli P, Merlini L, Nicolosi L, Finetti F, Braghetta P, Vuagniaux G, Dumont JM, et al.
British Journal of Pharmacology · 2009